AveronInstitute

Glossary · The journal

What Is Randomization in a Designed Experiment?

By the Averon Institute editorial team · September 30, 2025 · 2 min read

Randomization is the practice of running experimental trials in random order — decided by lot, not convenience — so that every influence the team did not plan for spreads itself evenly across the conditions being compared. It is the humblest idea in experimental design and the one doing the most work: an admission that unknown variables exist, paired with a mechanism that keeps them from voting as a bloc.

How it works

Processes drift. Machines warm through a shift, humidity climbs toward afternoon, operators tire, raw material ages in the queue. If the run order tracks a factor — all low-temperature runs in the morning, all high-temperature runs after lunch — then temperature and time of day are confounded, and no statistical method can pull them apart afterward. Random order breaks that alignment before it forms. Whatever drifts, drifts across both levels of every factor.

Randomization also underwrites the statistics themselves. The significance tests used to judge effects assume the noise in the data is unstructured, and random run order is what makes that assumption approximately true. It was R. A. Fisher’s insistence on this point in the 1920s that turned agricultural field trials from arguments into evidence.

A worked example

A heat-treating shop tests two quench oils by processing twenty parts with oil A in the morning and twenty with oil B in the afternoon. Oil B shows more distortion — but the furnace also ran hotter as the day went on, so the comparison is worthless: the oil and the furnace drift changed together. The corrected experiment interleaves the two oils in random order across the same day. Now the drift touches both oils alike, and whatever difference remains can be credited to the oil itself. The fix cost nothing but discipline — the shop simply had to resist the convenience of switching oil once instead of many times.

Practical pointers

  • Generate the run order with software or drawn lots — “mixed up by feel” is not random
  • If a factor is genuinely hard to randomize, say so and design around it deliberately rather than pretending
  • Randomize before the first run; reshuffling after results arrive is a different activity called cheating
  • Record the actual run order — it is the first thing to check when results look strange

Randomization is insurance against the variables you never thought to list.

Randomization appears early in our teaching because the idea is simple, but its full weight lands in the Black Belt program ($499, roughly 60 hours), where every designed experiment you build is expected to carry it. The free White Belt program — about six hours, ending in a 30-question exam — is where the vocabulary of sound evidence starts.

Put it into practice

Ready to make it official?

Our Six Sigma belt programs — White through Black — are self-paced, 100% online, and end in a proctored exam and a credential you can verify and share.